Skip to main content
NCBI home page

Linked Discoveries™ is an early-stage pilot for exploratory and evaluation purposes only.

Displayed results may be incomplete or inaccurate, do not represent the views of NLM or the U.S. Government, are provided for informational purposes only, and are not an endorsement. Contact the NLM Help Desk with questions.

Linked Discoveries™

Explore the literature surrounding a PubMed® citation

The initial phase of Linked Discoveries™ is an experimental pilot resource developed by the National Library of Medicine (NLM) that helps users explore how articles with PubMed® abstracts connect to the surrounding literature. Linked Discoveries creates neighborhoods of related articles, highlights shared conditions, genes, and chemicals across the neighborhood, and surfaces context like NIH funding, citation relationships, retractions, and reviews.

Linked Discoveries uses data from PubMed, along with related condition, gene, and chemical data linked from other NLM databases like Gene, MedGen, and PubChem®.

Explore Linked Discoveries using the example articles below or by finding the Linked Discoveries button on a PubMed abstract. See the User Guide to learn more.

View User Guide

Not sure where to start?

Try out Linked Discoveries using one of these sample “seed” articles.

In this section

  • Phenotype associations with genetic variants in age-related macular degeneration

    van Asten F, et al., Ophthalmology, 2018

    Explore this neighborhood

  • AI driven 3D subcellular RPE map discovers cell state transitions in establishment of apical-basal polarity

    Ortolan D, et al., NPJ Artif Intell, 2026

    Explore this neighborhood

  • CNS-targeted base editing of the major late-onset Tay-Sachs mutation alleviates disease in mice

    Allende ML, et al., J Clin Invest, 2025

    Explore this neighborhood

  • BilR is a gut microbial enzyme that reduces bilirubin to urobilinogen

    Hall B, et al., Nat Microbiol, 2024

    Explore this neighborhood

Supporting replication and reproducibility of biomedical research

Confidence in science depends in part on whether research findings are replicable and reproducible. It also depends on how individual findings relate to the broader body of evidence. Relevant studies can be difficult to discover. Prominent or highly cited findings may receive disproportionate attention while contradictory, null, or otherwise less prominent findings can be easier to miss.

Linked Discoveries is being developed to help address these challenges. In its initial phase, Linked Discoveries helps users explore the literature surrounding a PubMed citation by surfacing related articles, shared topics, retractions, reviews, and other scientific context. Future phases are intended to develop capabilities that more directly support replication and reproducibility by helping researchers discover, assess, and understand the broader body of evidence represented in the scientific literature.

Linked Discoveries is still under active refinement, with ongoing exploration of new features and functions planned for future releases. We invite you to try Linked Discoveries, explore a topic of interest to you, and share your thoughts using the Feedback button on any Linked Discovery page. Your feedback will help us shape where this pilot goes next!

Learn more at NIH